Neighbor’s Casual Kitchen – MECP2 Duplication Syndrome Fundraiser
End Wyatt’s wait for complete REVERSAL of MECP2 Duplication Syndrome.
His wish of walking, talking, eating, laughing can come true in the next two years.
*****Tuesday, November 15*****,~~~Neighbor’s Casual Kitchen~~~at Walnut Hill and Audelia
is donating 20% of the days food sales to 401Project.com.
Join Wyatt and his family for Live Music, Awesome Raffle Packages, Fabulous Food with friends.
Meet other affected families from north Texas.
The 401Project.com is a parent organized initiative with sights firmly fixed on a treatment. Global contributions are used solely for research. Money is directly deposited into the Rett Syndrome Research Trust MECP2 Duplication Syndrome Fund. RSRT is a registered non-profit organization. All donations are fully tax deductible. RSRT’s tax ID number is 26-0687439.
Donations can also be mailed to: Rett Syndrome Research Trust MECP2 Duplication Syndrome Fund, 67 Under Cliff Rd, Trumbull, CT, 06611. Please denote MECP2 Duplicaation Syndrome on memo line.
MECP2 Duplication Syndrome was discovered in 2005 by Dr. Huda Zoghbi during her research on Rett Syndrome. Both are caused by mutations in the MECP2 gene located on the X chromosome in every cell of the body. Wyatt’s syndrome results from a double dose of this gene. Recent studies indicate it is pivotal in regulating brain function by turning on and off other proteins. Prevalence may be 1.8 per 10,000 male births. Because it is a X-linked genetic disease, females are generally carriers of the syndrome and have a 50% chance of passing it to future children while males portray the common characteristics of very low muscle tone, developmental delay, autistic traits, recurrent severe respiratory infections, epilepsy, nonverbal communication, severe gastric reflux, constipation, and feeding issues. This progressive neurological disease in which symptoms worsen over time eventually leads to early death by the 20s.
The REVERSAL treatment research holding such promise is called ASO (antisense oligonucleotide therapy) and being conducted in Dr. Zoghbi’s lab at the Baylor College of Medicine in Houston, TX. More on this scientific breakthrough can be found in an article published in Nature magazine on November 25, 2005.